USA TODAY Sports' Week 1 NFL picks
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USA TODAY Sports - The Chiefs and/or Vikings can clinch divisional crowns, 49ers rookie QB Brock Purdy will make his first NFL start against Tom Brady + the Bucs and Baker Mayfield
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![NFL Week 1 Picks and Best Bets [Lions at Chiefs, Bills at Jets + MORE]](https://i.ytimg.com/vi/pCf9l2Zkpxs/maxresdefault.jpg "NFL Week 1 Picks and Best Bets [Lions at Chiefs, Bills at Jets + MORE]")
